China's national security agencies have discovered that foreign geographic information system software used in important industries in China has been collecting and transmitting geographic information data with some of the information collected involving state secrets, posing a serious threat to national security, China's Ministry of State Security said on Monday, noting that national security agencies will establish and improve a collaborative mechanism for data security protection to safeguard the protection of important national data.

Geographic information data are not only an important strategic data resource, but also a new production factor that can be widely applied in various industries, however, some organizations and individuals with ulterior motives have attempted to steal sensitive geographic information data using geographic information system software, according to an article released on the ministry's WeChat public account on Monday. 

Geographic information system software is professional software that has functions such as geographic information data collection, storage, analysis, management, and sharing. Such software has powerful functions and can annotate various types of geographic information collected on maps, and analyze and display them in various formats. Coordinate accuracy can even reach the centimeter level. 

However, some foreign organizations, institutions, and individuals have set their sights on the geographic information data, attempting to conduct intelligence espionage activities using geographic information system software, according to the WeChat article.

The methods of these foreign organizations and individuals include automatically connecting to foreign servers during software usage to collect user data without restrictions, and pre-installing backdoors in the software to facilitate network attacks and data theft.

Moreover,a small number of users have limited awareness of data security and mark high-precision geographic coordinates of urban pipelines, military targets, and sensitive units on maps, creating serious risks of leakage and potential irreparable losses, according to the article. 

It also noted that geographic data are a high-value intelligence resource and are a key target for foreign intelligence agencies' espionage activities. 

"By stealing high-precision geographic information data from our country, they can reconstruct three-dimensional topographic maps of specific areas in important fields such as transportation, energy, and military, providing crucial support for reconnaissance, surveillance, and military operations, posing a serious threat to our military security," the ministry said. 

Recently, national security agencies have discovered that foreign geographic information system software used in important domestic industries has been collecting and transmitting geographic information data, and some of the data are important and sensitive, even involving state secrets, posing a serious threat to our national security. 

In response, national security agencies, together with relevant departments, are conducting special investigations and governance of geographic information data security risks, guiding and assisting relevant units in conducting inspections and rectifications, and promptly eliminating major security risks such as data theft and leakage.

China's data security law stipulates that data processing activities should be carried out in accordance with the provisions of laws and regulations, establish and improve a comprehensive data security management system, organize data security education and training, adopt corresponding technical measures and other necessary measures to ensure data security.

When units and individuals engage in geographic information data collection and processing activities, they should choose secure and reliable geographic information system software, set strict access permissions based on the importance of the data, and ensure no sensitive information is available on the internet.

National security agencies will establish and improve a collaborative mechanism for data security protection in cooperation with relevant departments to jointly safeguard the protection of important national data, the Ministry of State Security said in the article. 

The ministry also warned that the theft, espionage, bribery, or illegal provision of data that arerelated to national security and interests by foreign organizations, institutions, individuals, or collusion with domestic organizations, institutions, individuals constitute espionage under Chinese law. 

Citizens who discover such behaviors can report them by calling the 12339 tip-off hotline, logging on to the www.12339.gov.cn , or reporting to the national security agencies through the official WeChat account, the article instructed. 

The Office for Safeguarding National Security of the Central People's Government in the Hong Kong Special Administrative Region (HKSAR) said on Thursday that it resolutely supports the Hong Kong police in arresting five fleeing anti-China figures in accordance with the law, and effectively preventing, stopping and punishing those who have fled to oppose the country and disrupt Hong Kong. 

The office said that "we must effectively safeguard the authority of the rule of law and consolidate the hard-won good situation in Hong Kong."

The Hong Kong Police Force's National Security Department announced on Thursday to place five more figures in exile into its warrant list, who are suspected of colluding with foreign or external forces including anti-government figures Joey Siu and Simon Cheng. 

In July, the police issued a HK$1 million ($128,000) bounty each for eight anti-government figures in exile, including Nathan Law Kwun-chung and Ted Hui Chi-fung. 

Cheng and others have long been engaged in anti-China and Hong Kong destabilization activities. After fleeing overseas, they continue to build platforms for disruptive activities in Hong Kong, spreading political rumors and "Hong Kong independence" fallacies about the country and Hong Kong, slandering Hong Kong's rule of law, and pleading for foreign forces to sanction Hong Kong or interfere in Hong Kong affairs, the office said.

They openly challenge the authority of the National Security Law (NSL) for Hong Kong and undermine Hong Kong's development. The Hong Kong Police, based on facts and in accordance with the law, have lawfully issued warrants for these fugitives involved in anti-China and Hong Kong destabilization activities. This aligns with the fundamental interests of Hong Kong, reflects the common will of society, and it's an inevitable requirement for the comprehensive and accurate implementation of the NSL for Hong Kong, a righteous act to safeguard national security in accordance with the law, and a necessary measure to ensure the prosperous and stable development of Hong Kong, the office said.

This issuance of warrant marks another lawful action following the July warrants against anti-government figure Kevin Yam and eight other fugitives for their leading roles in anti-China and Hong Kong destabilization activities. It targets five individuals suspected of committing crimes of inciting secession, inciting subversion of state power, and colluding with foreign or overseas forces to endanger national security, the office said. 

This demonstrates the Hong Kong Police's courageous responsibility, firm commitment to defending the authority of the NSL for Hong Kong, and unwavering determination to safeguard national security. It is believed that the Hong Kong police will take all necessary measures according to the law to hold these fugitives accountable for their crimes. 

They will also lawfully deal with those who assist, incite, or fund acts endangering national security, striking at the arrogance of these fugitives involved in anti-China and Hong Kong destabilization activities, the office said. 

The 33-year-old Cheng was suspected of inciting secession and colluding with foreign or overseas forces to endanger national security. Since August 2020, he, along with others, established political organizations and frequently advocated for "Hong Kong independence" on social media platforms, calling for foreign sanctions and hostile actions against Hong Kong government officials and judicial personnel. 

Cheng, a former employee at the British Consulate-General in Hong Kong, was detained by the mainland police at the West Kowloon high-speed rail station on August 8, 2019. Later, the Luohu public security in Shenzhen, South China's Guangdong, revealed that he had been "involved in prostitution activities multiple times," resulting in a 15-day administrative detention, according to media reports. 

The 31st FISU World University Games, after offering exciting competitions and diverse cultural exposure, concluded on Tuesday in Southwest China's Chengdu with a splendid ceremony that wrapped up shining moments during the Games and delivered wishes for a happier and brighter future.

The Chengdu FISU Games were not only a gathering for sports, but also a gathering to enhance mutual understanding and make friends, and the friendship will pass on among youth from all over the world with their traits of openness, inclusiveness, solidarity and vitality, analysts said.

The appearance of delegations features the process of a dove tree's growing from root to giant plant with lush branches and leaves. The dove-like flowers, a symbol of peace, then start to bloom.

The dove tree is a species indigenous to China which survived the ice age and its flower resembles a flying dove with two snow-white bracts. The ceremony incorporates the elements of the dove tree and its flowers to stress the resilience of life and the hope for everlasting peace.

Chinese State Councilor Shen Yiqin and FISU acting president Leonz Eder attended the ceremony.

The ceremony stage was designed based on a "cell phone" and captured the concept of livestreaming. Through the camera of a "livestreamer," young people from all over the world were able to be part of the FISU Games.

The master display presented 3D visual effects with naked-eye 3D technology, offering novel, amazing, special and delicate spectating experience.

After lowering the FISU flag along the playing of the FISU anthem, the flag was handed over to Rhine-Ruhr, host city of next FISU Games in 2025.

The FISU Games ran from July 28 to August 8 and featured 269 events across 18 sports. The Chinese delegation participated in all 18 sports of the games and claimed 103 gold medals, 40 silvers and 35 bronzes in total, ranking on top of the medal tally.

Besides performance on the competition ground, China's performance in terms of hosting this international event is also well recognized.

"The preparations and setup of the venues are just unbelievable. Everything has been running smoothly and the competitions are going very well. We can only praise the organizing committee for the great work it's done," Eder said in an earlier exclusive interview with the Global Times.

Making friends

For the participants, from athletes and coaches to staff and volunteers, the past weeks have made Chengdu, known for its tasty cuisines, adorable pandas and a leisure lifestyle, an unforgettable place where they've shed sweat and tears, challenged themselves and make breakthroughs, and more importantly, make friends beyond borders, analysts said.

One touching moment which can elucidate the sportsmanship of the youth event happened on Friday. When Uganda's badminton player Amos Muyanja broke his racket without a replacement, his competitor from China Wang Zhengxing offered Muyanja a backup racket.

The FISU Games organizer wrote on Twitter that "we unite to push our limits and inspire each other… We wish all the participants not only to take home victories but also friendship and cherished memories!"

Azerbaijan badminton player Agil Gabilov told the Global Times on Tuesday that Chengdu has been a great experience for him. He made friends with athletes and volunteers and was impressed by the friendliness he received.

Brazilian swimmer Fernanda Gomes Celidonio said that volunteers at the Chengdu Games made her feel "at home."

Athletes including German volleyball player Yann Bohme got a birthday surprise as after a match, the cheering squad and mascot Rongbao wished him happy birthday and the audience sang in chorus the birthday melody for him.

Athletes also received special gifts, including 3D-printed figurine and local artifacts such as palm fiber weavings and embroidery badges, according to media reports.

The Games also provide a great platform for cultural exchanges other than competition, which Zambian tennis player Esther Sakala appreciated a lot.

Sakala, as a lover of art and an artist herself, was excited to meet those crafty and talented people and see their skills. She had a chance to paint a cup which was later given as a gift and Sakala said she "Loved it so much."A range of Chinese cultural elements, from handicrafts to musical instruments, have intrigued FISU Game participants at a culture fair held next to the Games Village.

Youth spirit

On and off the competition ground, youth across the world are demonstrating the spirit of openness, inclusiveness and solidarity, igniting a world of division and turbulence, analysts noted.

The Chengdu FISU Games were postponed twice due to the COVID-19 pandemic, and this successful holding marked the resumption of face-to-face communication and exchanges among youth via sports and can leverage more interactions in other fields, such as culture, they said.

Li Haidong, a professor with the China Foreign Affairs University, told the Global Times on Tuesday that sport can be an easy bridge to connect people from different countries and regions and help them build friendship.

The FISU World University Games in Chengdu are a precious opportunity for athletes and people from all around the world to deepen mutual understanding and trust, which will also lay the foundation for closer cooperation and solidarity, Li noted.

FISU Universiade was first held during the Cold War in 1959. It not only encourages young people to adopt a healthy lifestyle, but also seeks to promote young people communicating across cultural, political and religious barriers through sports, Ren Hai, a professor at the Olympic Research Center of Beijing Sports University, told the Global Times.

When the world is experiencing uncertainty and turbulence, China hopes to deliver a message of peace, communication and cooperation through this gathering of young people, who represent hope and the future, analysts said.

Eder, the acting president of the FISU, has visited China more than 20 times and observed the country's fast economic development, as well as its increased confidence and openness. "I can feel the country's readiness to cooperate with many countries whether they come from the East, West, North, or South," Eder said.

The Asia-Pacific Regional Director of the International Federation of Red Cross and Red Crescent Societies (IFRC) Alexander Matheous has described the situation of quake-affected people in west Afghanistan's Herat province as extremely impoverished, and said the body would continue to assist them.

"We will continue to provide relief items in the coming days. Our plan is to work with the Afghan Red Crescent on suitable shelters for the people to live in the short term," Matheous told Xinhua in a recent exclusive interview.

The IFRC has already provided humanitarian assistance such as blankets, non-food items and hygiene kits, the official said, adding the affected families need more support.

The official who visited the quake-stricken areas in Herat also noted that the quake-affected people need support to rebuild their homes and live in the long term.

Two deadly quakes, each with a magnitude of 6.2 on the Richter scale, followed by several aftershocks, rocked west Afghanistan with an epicenter in the Zanda Jan district of Herat province last Saturday, and left at least 2,053 dead and thousands more injured.

Another tremor measuring 6.3 on the Richter scale jolted Herat on Wednesday, killing one person, injuring more than 150 others, and causing property damages.

"More than 2,000 people and over 2,000 homes are destroyed," the official said, adding most of the victims are women and children, and the affected families have lost what they had.

"People need food, water, shelter, medical camp...It was a very dramatic and tragic disaster for the people," the official told Xinhua.

Praising the contribution of the Afghan Red Crescent Society in tackling the problems of the quake-affected people, the official said that it was the first humanitarian organization to be present after the disaster.

"We will support the Afghan Red Crescent to work not just in this relief phase, but also in the months to come to rebuild the houses and people's livelihoods," Matheous emphasized.

The Investment Office of the Presidency of the Republic of Turkey held a reception at the Turkish Embassy in Beijing with the aim of boosting investment cooperation with China. The event, as a part of their "Turkish Century Investment Reception" series, saw more than 500 business people and investors from China's leading companies to attend. 

Turkish Ambassador to China Ismail Hakkı Musa, President of the Investment Office of the Presidency of the Republic of Turkey Ahmet Burak Daglioglu, and the Silk Road Fund Chairwoman Zhu Jun were also in attendance. 

"This year, we are celebrating the 500th anniversary of the establishment of the Turkish Ministry of Foreign Affairs, the 100th anniversary of the founding of the Republic of Turkey and the 52nd anniversary of the establishment of diplomatic ties between Turkey and China. From e-commerce to telecommunications, from renewable energy to electric vehicles, from cloud technology to the defense industry, we have forged new partnerships with China in a wide range of areas," the ambassador said. 

In addition, the guests sampled sumptuous Turkish cuisine and discussed cooperation and investment opportunities.

Editor's Note:
Some observers believe that China-UK relations are at its lowest point, but Alistair Michie, secretary general of the British East Asia Council and winner of the Chinese Friendship Award Medal in 2013, told the Global Times in an exclusive interview that he does not agree with this assessment. Instead, it would be highly desirable for all nations to have golden eras of understanding with China, Michie said, noting that one of the key issues is that a significant number of UK politicians are heavily influenced by the US. He also said that the UK should consider joining the Belt and Road Initiative (BRI) as well as other initiatives that can move both countries in a more positive direction. Global Times reporters Xie Wenting and Bai Yunyi (GT) talked with Michie to get his insightful opinions on China-UK relations, the BRI and more. 

GT: The Chinese version of the book Consensus or Conflict? China and Globalization in the 21st Century co-edited by you has been published recently and distributed in China. Could you tell us why you wanted to compile such a book? What feedback have you received?

Michie: I was motivated to do the book in 2020. What I felt was that at that time, there was an opportunity for the world to gather together and deal with the challenge of the COVID-19 pandemic, in the same way that the world dealt with the global financial crisis in 2008. Back in 2008, the G20 played a particularly crucial role in stabilizing what was a very serious global financial crisis. The way the economic crisis unfolded in 2008 posed extreme danger for the world. So, at the start of 2020, I hoped that the world and nations would gather together in a way that could lead to the development of solutions, where the world would unite toward a common destiny.

I was also greatly influenced by the Chinese leader's repeated calls over many years for the world to move forward with mutual understanding and mutual respect toward a community of common destiny. I believed that the only way to effectively and efficiently address global challenges, such as the COVID-19 pandemic, was through collective action and a shared purpose. 

This motivation laid the foundations for the book. I was pleasantly surprised that we were able to gather over 30 distinguished writers from around the world, who provided their perspectives on why it is crucial for the world to address issues like pandemics through consensus rather than conflict in terms of global matters. This served as the motivation and genesis of the book.

Regarding the feedback, I was particularly pleased that we gathered 10 recommendations from distinguished global leaders, printed in the front of the book. They emphasized the importance of reading this book as it promotes consensus over conflict. These high-level individuals from around the world recognized the crucial theme and message of the book. However, the outcome has been disappointing. Since the English version was published in September 2021, the world has significantly shifted toward conflict and away from consensus. 

GT: Are you disappointed with the direction in which the world is progressing?

Michie: I am deeply frustrated because, since publishing the book with hopes of achieving consensus, the world has instead been steadily moving toward conflict. This is a critical issue for humanity, as there are numerous threats such as climate change, future pandemics, nuclear concerns, challenges in biosciences, and artificial intelligence. These issues require nations to act together in the interest of all humanity, but unfortunately, consensus is lacking. The lack of cooperation is deeply concerning as it can lead to misunderstandings, miscalculations, and catastrophic conflicts. It is a dangerous world. While I find some satisfaction in expressing these views and highlighting the dangers, I am still deeply frustrated by the world's trajectory toward conflict rather than consensus.

By nature, I have always been positive that humanity will find a solution. However, it is also crucial to be realistic. One issue I addressed in my book is the communication crisis our world is facing. Different nations struggle to explain their perspectives, largely due to the fact that we think differently. For instance, China, with nearly 20 percent of the world's population, has a distinct way of thinking compared to America and Europe.

Therefore, the lack of effective communication is causing a crisis in understanding different perspectives and points of view. 

GT: Not long ago, you mentioned that there are many Americans who have closed their minds and turned a blind eye to significant global changes, which is "extremely dangerous" for the world. What specific "significant global changes" do you mean? Could you elaborate on the potential dangers it poses to the world if Americans turned a blind eye to these changes?

Michie: One of the major dangers that the world faces is the way many Americans are thinking today. The US holds a very dominant position in global governance despite only representing 4 percent of the world's population. This massive influence held by a small number of people is frustrating for the rest of the world. Additionally, it is also frustrating that many Americans tend to look inward.

For example, many Americans do not accept that there is a threat and danger from climate change. They are not actively dealing with other serious global threats like nuclear issues, artificial intelligence, or biosciences. This turning inward is extremely dangerous because these are issues that affect all humanity and the world. 

Additionally, we have a situation where the US political system is deeply fractured, and this creates great dangers for the world going forward.

GT: UK Foreign Secretary James Cleverly recently paid a visit to China and he said that it would not be "credible" to disengage with China. However, the British parliament referred to Taiwan as an "independent country" in an official document for the first time, coinciding with Cleverly's visit. What's your perspective on it? In recent years, the UK's attitude toward China has undergone major changes. What do you think are the reasons behind this?

Michie: I think what we need to do is to be very careful about making statements that can cause anger between countries like this one. As I mentioned earlier, we are currently facing a communication crisis, and what we truly need is more dialogue and discussion to foster an intelligent conversation among nations. Fortunately, there are many people in the UK who are working toward creating that environment. However, there are also individuals in the UK who are not interested in engaging in an intelligent dialogue; they have their own agendas. 

One of the issues we face is that a significant number of UK politicians are heavily influenced by the US, which aims to hinder China's progress. On the other hand, there are US politicians who are also striving to build an intelligent dialogue. Nonetheless, this situation is extremely dangerous, particularly given the current communication crisis and social media. It is so easy to have many comments that can be misunderstood and create conflicts and misunderstandings on social media. Therefore, it is crucial to engage in as much dialogue as possible to foster an intelligent conversation among nations.

GT: Do you think the current UK policy toward China is too influenced by Washington?

Michie: I believe that one of the root problems is that the US still wishes to be the hegemonic leader of the world, despite comprising only 4 percent of the global population. It has convinced itself that this is the right path to follow. However, due to many Americans focusing inward and ignoring critical global issues such as climate change and other threats, a significant problem arises for the world.

GT: Some observers have said that China-UK relations are at the lowest point. Do you agree with this? Do you think the bilateral relations can get back to a golden era?

Michie: No, I don't think we're at the lowest point at all because one of the most important trends in the last two decades is the tens of thousands of Chinese students who have come to the UK to study. I think that we rank second or third in the world in terms of attracting Chinese nationals to come and study in our education system. That is the kind of foundation-laying for intelligent dialogue that I have argued is so important in creating the kind of understanding that will lead to consensus.

I am very hopeful that this student exchange will help to create a more peaceful and sustainable world in the future. 

It would be highly desirable for all nations to have golden eras of understanding with China. Unfortunately, at the moment, we are not moving in that direction, but we must do everything in our power to engage in intelligent dialogue and create understanding, so that we can move toward what you describe as a golden era of relationships. This will enable us to address the significant challenges facing humanity.

GT: Many Western politicians have recently been talking about so-called decoupling from China. What's your take on it? Is it possible for the West to decouple from China?

Michie: I believe that decoupling and de-risking are not the right direction. What we must do is focus much more on creating an intelligent dialogue so that we can understand each other better and avoid moving toward conflict. It is absolutely crucial to move away from de-risking and decoupling, as I argue that the fundamental need is to create a much deeper and better understanding. The only way we can solve the crises facing all of humanity is by coming together in consensus and creating mutual understanding and respect, in order to move toward a community of common destiny. That is the only way, but it poses a huge challenge for the world.

GT: This year marks the 10th anniversary of the Belt and Road Initiative (BRI). How do you view the development of the BRI over the past decade and its future prospects?

Michie: I think the Belt and Road Initiative (BRI) has been a hugely important initiative by China because it serves as a channel for creating human connection. Communication can take various forms, such as infrastructure development including roads, airports, and harbors, which facilitate the exchange of ideas and foster understanding. This initiative also promotes intelligent dialogue, and China possesses the expertise to extend these infrastructure developments worldwide.

So, I believe it is a hugely important contribution toward improving global governance. At the moment, global governance faces a challenge as it is dominated by just 14 percent of the global population, which includes 4 percent in the US and under 10 percent in Europe. It is understandable that the rest of the world becomes frustrated when such a small percentage of the world's population holds such a dominant influence. Initiatives like the BRI are a way of striving toward creating a broader form of global governance that can lead us toward international consensus. 

I hope that the BRI will continue to evolve, fostering exchanges and understanding that can truly guide us toward a more peaceful and sustainable world.

GT: Do you think that the UK should consider joining the BRI?

Michie: I believe that everything should be considered in any way forward that we can create in dialogue and understanding, in order to create a world that is moving toward a common destiny. We can only solve the incredibly serious and dangerous challenges that the world faces if we move toward consensus. Initiatives like the BRI should be considered, as well as anything that can move us in a more positive direction.

Waterlily beetles (Galerucella nymphaeae) literally fly across water, high speed videography and a bit of mathematical modeling reveals.

The beetles have a combination of hydrophobic hairs that line their legs and hydrophilic claws that grip the surface of water without getting too wet. Prior to “take off,” the insects lift their middle pair of legs. Then, the insects beat their wings extremely fast and fly horizontally across a pool of water. It looks a lot like water-skiing.
In lab tests, waterlily beetles reached 0.5 meters per second — without an active brake system. Surface tension keeps the insects afloat, they found. The insects create ripples in the water, which generates drag at speeds greater than 0.23 meters per second (more drag than when the beetles just fly through air). Thus, for these beetles, skiing across a pond at breakneck speeds costs a lot of energy and requires greater wing thrust than normal flying. However, this mode of getting around could be more advantageous for foraging and help them avoid underwater predators like fish, the researchers speculate March 2 in the Journal of Experimental Biology.

CERN’s Large Hadron Collider is in standby mode after a 66-kilovolt/18-kilovolt electrical transformer suffered a short circuit April 29 at 5:30 a.m. Central European Time. The culprit: A small wild animal, believed to be a weasel, gnawing on a power cable.

“The concerned part of the LHC stopped immediately and safely, though some connections were slightly damaged due to an electrical arc,” Arnaud Marsollier, who leads CERN’s press office, wrote in an e-mail to Science News.

Sadly, the weasel did not survive the event, but the LHC should be back online soon. “It may take a few days to repair but such events happened a few times in the past and are part of the life of such a large installation,” Marsollier writes. The power outage comes just as the LHC is preparing to resume collecting data.

This isn’t the the first time an odd event has stalled operations at the particle collider outside Geneva on the Swiss-French border. In 2009, a piece of bread (supposedly a baguette dropped by a bird or from an airplane) interrupted a power installation for an LHC cooling unit.

A popular type of heartburn medicine could hasten wear and tear of blood vessels.

Proton pump inhibitors, or PPIs, gunk up cells that typically line the veins and arteries like a slick coat of Teflon, researchers report May 10 in Circulation Research. Excess cellular junk ages the cells, which could make blood vessels work less smoothly.

The results, though controversial, are the first inkling of evidence that might explain why PPIs have recently been linked to so many different health problems, from heart attacks to dementia.
“The authors present a compelling story,” says Ziyad Al-Aly, a nephrologist at the Veterans Affairs Saint Louis Health Care System in Missouri. It begins to outline how using PPIs could spell trouble later on, he says. But Al-Aly notes that the study has one big limitation: It was done in cells, not people.

Gastroenterologist Ian Forgacs from King’s College Hospital in London agrees. Drawing conclusions about humans from cells grown in the lab requires “a huge leap of faith,” he says. So far, scientists have found only correlations between PPIs and their alleged side effects. “We need to know whether these drugs really do cause dementia and coronary disease and renal disease,” he says.

In the last few decades, proton pump inhibitors have emerged as a kind of wonder drug for heartburn. The drugs switch off molecular machines that pump acid into the stomach. So less acid surges up to burn the esophagus.

In 2012, nearly 8 percent of U.S. adults were taking prescription PPIs, according to a survey published last year in JAMA. (Some PPIs are also available over-the-counter.) Many people use PPIs for longer than they’re supposed to, says study coauthor John Cooke, a cardiologist at Houston Methodist Research Institute in Texas. “These are very powerful drugs­ — they’re not Tums,” he says. “They have side effects.”

Several of these side effects are still under debate. And if PPIs do increase the risk of dementia, say, or kidney disease, no one knows how. So Cooke and colleagues explored what chronic exposure to the drugs, which travel through the bloodstream, does to cells lining the blood vessels.
Human cells treated with a PPI called esomeprazole (sold as Nexium) seemed to age faster than untreated cells, the researchers found. The cells lost their youthful shape and instead “looked kind of like a fried egg,” Cooke says. They also lost the ability to split into new cells, among other signs of aging.

Cooke traced the rapid aging to mishaps in acid-filled cellular chambers called lysosomes. These chambers act as tiny garbage disposals; they get rid of junk like broken-down proteins. But PPIs, which work so well at shutting down acid production in the stomach, also seemed to shut down the acidic garbage disposals, too, the researchers found. That caused proteins to pile up, forming “little heaps of rubbish,” Cooke says.

Mucking with blood vessels’ lining could trigger all sorts of problems. For instance, instead of gliding easily through, platelets and white blood cells could get hung up, sticking to vessel walls like Velcro. “That’s how hardening of the arteries starts,” Cooke says.

The next step is to see if similar damage occurs in people. Doctors and regulatory agencies should take a second look at the widespread use of PPIs, too, Cooke says. “There’s enough data now that we have to be very cautious in our use of these agents.”

But some researchers think PPIs are getting a bum rap. “Everybody and their mother now want to hammer PPIs,” says gastroenterologist David Metz of the University of Pennsylvania. “It’s unfortunate because they’re spectacular drugs and they save people’s lives.”

The real question, Al-Aly says, is whether the benefits outweigh the risks.

In the scorching heat of the Kalahari Desert, some birds still manage to keep their cool.

Thermal imaging reveals that the southern yellow-billed hornbill (Tockus leucomelas) vents heat from its beak, a phenomenon previously observed in toco toucans (Ramphastos toco). A team of South African researchers snapped infrared photos of 18 hornbills on a farm in the southern edge of the desert at temperatures from 15° to 45° Celsius.

When air temperatures hit 30.7° Celsius, the difference between beak surface temperature and air temperature spikes — indicating the birds were actively radiating heat through their beaks. At most, the birds lost about 25.1 watts per square meter through their beaks. Hornbills probably manage this cool trick by dilating the blood vessels to increase flow in their uninsulated beaks, the team writes May 18 in PLOS ONE.

Toucans lose about 60 percent of their total heat loss through their beaks, but hornbills only shed up to 20 percent of their heat loss through this method. The researchers chalk that difference up to larger beak-to-body-size in toucans.